TP53 is the most frequently mutated gene in cancer. The p53 protein activates transcription of genes that promote cell cycle arrest or apoptosis. or regulate cell metabolism and other processes . Missense mutations in TP53 abolish specific DNA binding of p53 and allow evasion of apoptosis and accelerated tumor progression. https://herbsdailyes.shop/product-category/pillows/
Targeting of mutant p53 and the cellular redox balance by APR-246 as a strategy for efficient cancer therapy
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