Sliding-window analysis has widely been used to uncover synonymous (silent. d(S)) and nonsynonymous (replacement. d(N)) rate variation along the protein sequence and to detect regions of a protein under selective constraint (indicated by d(N)d(S)). The approach compares two or more protein-coding genes and plots estimates d(/\)(S) and d(/\)(N) from each sliding window along the sequence. https://www.jmannino.com/super-super-Bamboo-Cloth-Baby-Nappy-White-amazing-save/
The trouble with sliding windows and the selective pressure in BRCA1.
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