Abstract Background Reduced representation bisulfite sequencing (RRBS) was developed to measure DNA methylation of high-CG regions at single base-pair resolution. and has been widely used because of its minimal DNA requirements and cost efficacy; however. the CpG coverage of genomic regions is restricted and important regions with low-CG will be ignored in DNA methylation profiling. T... https://foldlyers.shop/product-category/drills/